Document Detail

Cognitive and neurobehavioral functioning after mild versus moderate traumatic brain injury in older adults.
MedLine Citation:
PMID:  11311038     Owner:  NLM     Status:  MEDLINE    
This study evaluated the early cognitive and neurobehavioral outcomes of older adults with mild versus moderate traumatic brain injury (TBI). Thirty-five patients who were age 50 years and older and sustained mild or moderate TBI were prospectively recruited from acute care hospitals. Patients were administered cognitive and neurobehavioral measures up to 2 months post-injury. Demographically comparable control participants received the same measures. Patients and controls did not have previous histories of substance abuse, neuropsychiatric disturbance, dementia, or neurologic illness. Moderate TBI patients performed significantly poorer than mild TBI patients and controls on most cognitive measures, whereas the mild patients performed comparably to controls. In contrast, both mild and moderate patients exhibited significantly greater depression and anxiety/somatic concern than controls. The results indicate that the classification of TBI as mild versus moderate is prognostically meaningful as applied to older adults. The findings extend previous investigations in young adults by demonstrating a relatively good cognitive outcome on objective measures, but subjective complaints after a single, uncomplicated mild TBI in older persons.
F C Goldstein; H S Levin; W P Goldman; A N Clark; T K Altonen
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of the International Neuropsychological Society : JINS     Volume:  7     ISSN:  1355-6177     ISO Abbreviation:  J Int Neuropsychol Soc     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-04-19     Completed Date:  2001-05-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9503760     Medline TA:  J Int Neuropsychol Soc     Country:  England    
Other Details:
Languages:  eng     Pagination:  373-83     Citation Subset:  IM    
Department of Neurology, Emory University School of Medicine and Wesley Woods Center of Emory University, Atlanta, Georgia 30329, USA.
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MeSH Terms
Aged / psychology*
Behavior / physiology*
Brain Injuries / psychology*
Cognition / physiology*
Magnetic Resonance Imaging
Middle Aged
Neuropsychological Tests
Prospective Studies
Tomography, X-Ray Computed
Grant Support
H133G30051//PHS HHS; R49/CCR612707-01//PHS HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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