| Cognitive loss and recovery in long-term alcohol abusers. | |
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MedLine Citation:
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PMID: 6838323 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The nature of the memory and visuospatial defects associated with chronic alcoholism, and the recovery of these functions, were investigated in a large group of alcoholic men and well-matched nonalcoholic controls. Both young and old alcoholics displayed significant impairments on tasks requiring the learning of novel associations and the holding of information in memory over longer delay intervals. The recovery of cognitive skills was found to depend on the length of abstinence and the particular behavioral functions examined. Whereas psychomotor skills and short-term memory improved significantly with prolonged abstinence, long-term memory was impaired even after seven years of continuous sobriety. We propose that recovery of short-term memory reflects reestablishment of cortical functioning, while the persistent long-term memory defect indicates more permanent damage to diencephalic structures. |
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Authors:
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J Brandt; N Butters; C Ryan; R Bayog |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Archives of general psychiatry Volume: 40 ISSN: 0003-990X ISO Abbreviation: Arch. Gen. Psychiatry Publication Date: 1983 Apr |
Date Detail:
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Created Date: 1983-05-05 Completed Date: 1983-05-05 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372435 Medline TA: Arch Gen Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 435-42 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alcohol Drinking Alcoholism / physiopathology, psychology*, rehabilitation Cerebral Cortex / physiopathology Cognition Disorders / physiopathology, psychology* Diencephalon / physiopathology Humans Male Memory Disorders / physiopathology, psychology Memory, Short-Term Middle Aged Paired-Associate Learning Psychomotor Performance |
| Grant Support | |
ID/Acronym/Agency:
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AA-00187/AA/NIAAA NIH HHS; F31-MH 08148-01/MH/NIMH NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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