| Cognitive insight in individuals at clinical high risk for psychosis. | |
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MedLine Citation:
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PMID: 23343417 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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AIM: Reduced cognitive insight has been associated with psychotic symptoms, in particular with the presence of delusions; however, there is little information about whether such reductions are present in at-risk individuals prior to the onset of threshold psychotic symptoms. METHOD: We conducted a cross-sectional comparison of cognitive insight (as indexed by the Beck Cognitive Insight Scale) in 62 help-seeking individuals at clinical high risk for psychosis, Fifty-nine individuals with schizophrenia-spectrum disorders and 37 healthy controls (HC). In patients, we evaluated associations of insight with positive symptoms, including later transition to psychosis in high-risk patients. RESULTS: Individuals with schizophrenia reported significantly higher self-certainty scores than the at-risk patients and HCs, with the at-risk patients scoring intermediate to the individuals with schizophrenia andcontrols. Similarly, individuals with schizophrenia scored significantly higher on self-reflectiveness, with no differences between the at-risk patients and controls. In individuals with schizophrenia, delusions were significantly correlated with self-certainty. In at-risk patients, cognitive insight was not associated with positive symptom severity and did not differentiate those at-risk patients who later developed psychosis from those who did not. However, post hoc analyses suggested that at-risk patients with marked unusual thought content (approaching threshold psychosis) had lower self-reflectiveness; whereas those with high suspiciousness had significantly higher self-certainty. CONCLUSIONS: The findings are discussed in the context of normal developmental processes occurring during adolescence, their putative links to neurobiological functioning, and their implications for treatment and future research. |
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Authors:
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David Kimhy; Lauren Jobson-Ahmed; Shelly Ben-David; Lisa Ramadhar; Dolores Malaspina; Cheryl M Corcoran |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-24 |
Journal Detail:
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Title: Early intervention in psychiatry Volume: - ISSN: 1751-7893 ISO Abbreviation: Early Interv Psychiatry Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101320027 Medline TA: Early Interv Psychiatry Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2013 Wiley Publishing Asia Pty Ltd. |
Affiliation:
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Department of Psychiatry, Columbia University, New York, New York, USA; Center of Prevention and Evaluation, New York State Psychiatric Institute, New York, New York, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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