Document Detail


Cognitive insight in individuals at clinical high risk for psychosis.
MedLine Citation:
PMID:  23343417     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
AIM: Reduced cognitive insight has been associated with psychotic symptoms, in particular with the presence of delusions; however, there is little information about whether such reductions are present in at-risk individuals prior to the onset of threshold psychotic symptoms. METHOD: We conducted a cross-sectional comparison of cognitive insight (as indexed by the Beck Cognitive Insight Scale) in 62 help-seeking individuals at clinical high risk for psychosis, Fifty-nine individuals with schizophrenia-spectrum disorders and 37 healthy controls (HC). In patients, we evaluated associations of insight with positive symptoms, including later transition to psychosis in high-risk patients. RESULTS: Individuals with schizophrenia reported significantly higher self-certainty scores than the at-risk patients and HCs, with the at-risk patients scoring intermediate to the individuals with schizophrenia andcontrols. Similarly, individuals with schizophrenia scored significantly higher on self-reflectiveness, with no differences between the at-risk patients and controls. In individuals with schizophrenia, delusions were significantly correlated with self-certainty. In at-risk patients, cognitive insight was not associated with positive symptom severity and did not differentiate those at-risk patients who later developed psychosis from those who did not. However, post hoc analyses suggested that at-risk patients with marked unusual thought content (approaching threshold psychosis) had lower self-reflectiveness; whereas those with high suspiciousness had significantly higher self-certainty. CONCLUSIONS: The findings are discussed in the context of normal developmental processes occurring during adolescence, their putative links to neurobiological functioning, and their implications for treatment and future research.
Authors:
David Kimhy; Lauren Jobson-Ahmed; Shelly Ben-David; Lisa Ramadhar; Dolores Malaspina; Cheryl M Corcoran
Related Documents :
24532007 - A phase 2 trial of the gsk-3 inhibitor tideglusib in progressive supranuclear palsy.
24224787 - Effectiveness of a peer-led self-management programme for people with schizophrenia: pr...
24555047 - Internet-delivered eye movement desensitization and reprocessing (iemdr): an open trial.
24113727 - Developing complex interventions: lessons learned from a pilot study examining strategy...
7814347 - Is there a role for neuroleptics in bipolar depression?
20543997 - Imitate: an intensive computer-based treatment for aphasia based on action observation ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-24
Journal Detail:
Title:  Early intervention in psychiatry     Volume:  -     ISSN:  1751-7893     ISO Abbreviation:  Early Interv Psychiatry     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101320027     Medline TA:  Early Interv Psychiatry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 Wiley Publishing Asia Pty Ltd.
Affiliation:
Department of Psychiatry, Columbia University, New York, New York, USA; Center of Prevention and Evaluation, New York State Psychiatric Institute, New York, New York, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Long term toxicity and prognostic factors of radiation therapy for secreting and non-secreting pitui...
Next Document:  Evaluation of Xpert MTB/RIF and MODS assay for the diagnosis of pediatric tuberculosis.