Document Detail

Cognitive impairment in heart failure with Cheyne-Stokes respiration.
MedLine Citation:
PMID:  11119454     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To document the degree of cognitive impairment in stable heart failure, and to determine its relation to the presence of Cheyne-Stokes respiration during sleep. SUBJECTS: 104 heart failure patients and 21 healthy normal volunteers. METHODS: Overnight oximetry was used (previously validated as a screening tool for Cheyne-Stokes respiration in heart failure). Cognitive function was assessed using a battery of neuropsychological tests. Left ventricular function was assessed by echocardiography. RESULTS: Heart failure patients performed worse than the healthy volunteers in tests that measured vigilance. Reaction times were 48% slower (0.89 (0.03) s v 0.60 (0.05) s p < 0.005) and they hit twice as many obstacles on the Steer Clear simulator (75 (6.4) v 33 (4.6); p < 0.005). Cognitive impairment within the heart failure group was unrelated to either the presence of Cheyne-Stokes respiration, the degree of left ventricular dysfunction, or indices of nocturnal oxygenation. CONCLUSIONS: Vigilance was impaired in heart failure but this did not appear to be related to the presence of Cheyne-Stokes respiration during sleep. Impaired vigilance as measured on the Steer Clear test has been associated with an increased risk of motor vehicle accidents. The issue of fitness to drive in heart failure requires further attention.
A D Staniforth; W J Kinnear; A J Cowley
Related Documents :
15820464 - A cumulative analysis of an individual surgeon's early experience with elective open ab...
16837084 - Autoimmunity in myocardial infarction.
19949714 - Phlebotomies as a treatment of serious heart failure due to haemochromatosis: a case re...
20424964 - Myocardial ischemia in patients with diastolic dysfunction and heart failure.
20506154 - Improving myocardial salvage in late presentation acute st-elevation myocardial infarct...
6507974 - Renal infarction associated with intravenous cocaine use.
Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  85     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2000-12-26     Completed Date:  2001-03-15     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  18-22     Citation Subset:  IM    
Department of Cardiovascular Medicine, Queens Medical Centre, Nottingham, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cheyne-Stokes Respiration / complications*
Cognition Disorders / diagnosis*,  etiology*
Heart Failure / complications*
Neuropsychological Tests
Reaction Time
Ventricular Function, Left

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Outcome of hypospadias repair using the tubularized, incised plate urethroplasty.
Next Document:  Pulmonary venous flow velocity patterns in 404 individuals without cardiovascular disease.