Document Detail


Cognitive deficits in essential tremor consistent with frontosubcortical dysfunction.
MedLine Citation:
PMID:  18608666     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Essential tremor (ET) is increasingly thought to involve a heterogeneous group of patients, with some also exhibiting symptoms of Parkinson's disease (PD), including cognitive deficits. The goal of this study was to utilize a broad battery of neuropsychological measures to compare the cognitive function of 33 ET patients with that of 33 matched PD patients and 21 normal controls. Results indicated that the ET group performed significantly worse than controls across multiple cognitive domains, but performed remarkably similar to PD patients, consistent with frontosubcortical dysfunction.
Authors:
Christopher I Higginson; Vicki L Wheelock; Dawn Levine; David S King; Conrad T E Pappas; Karen A Sigvardt
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2008-02-15
Journal Detail:
Title:  Journal of clinical and experimental neuropsychology     Volume:  30     ISSN:  1744-411X     ISO Abbreviation:  J Clin Exp Neuropsychol     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2010-03-12     Completed Date:  2010-06-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8502170     Medline TA:  J Clin Exp Neuropsychol     Country:  England    
Other Details:
Languages:  eng     Pagination:  760-5     Citation Subset:  IM    
Affiliation:
Department of Psychology, Loyola College in Maryland, Baltimore, MD 21210-2699, USA. cihigginson@loyola.edu
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Case-Control Studies
Cerebral Cortex / physiopathology*
Cognition Disorders / etiology*
Essential Tremor / complications*
Female
Humans
Male
Middle Aged
Multivariate Analysis
Neuropsychological Tests
Grant Support
ID/Acronym/Agency:
NS39121/NS/NINDS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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