| Cognitive and behavioral characteristics of children with Dravet syndrome: an overview. | |
| | |
MedLine Citation:
|
PMID: 21463277 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
We report an overview on early development of children with Dravet syndrome. After a historical outline of literature data, we refer to an Italian multicentric project, partially still in course. Because in the first year of life development seems impaired in Dravet syndrome as studies on precognitive abilities would show, defects in early development of visual function were detected heralding the subsequent cognitive decline. The delay of cognitive development, due to stagnation rather than a real deterioration, begins after the second year of life, although the age of onset varies. The extreme variability of development phenotype is confirmed and widened including also cognitive decline and severity of different defects of neuropsychological abilities as well as behavioral problems, especially associated with the cognitive decline. Mechanisms underlying neurodevelopment disorders and possible role of genetics are discussed. |
| | |
Authors:
|
Francesco Guzzetta |
Related Documents
:
|
1456257 - Spontaneous chylothorax in noonan syndrome. treatment with prednisone. 20963467 - Tako-tsubo cardiomyopathy in a patient with bilateral lesions in the dorsal medulla. 8874917 - The anaesthetic management of a patient with emery-dreifuss muscular dystrophy. 7491317 - Preexcitation in hypertrophic cardiomyopathy: a case of a fasciculoventricular mahaim f... 251167 - Ventricular fibrillation in wolff-parkinson-white syndrome, type a. 21589837 - Hyperuricemia in obese children and adolescents: the relationship with metabolic syndrome. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Epilepsia Volume: 52 Suppl 2 ISSN: 1528-1167 ISO Abbreviation: Epilepsia Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-04-05 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
|
Languages: eng Pagination: 35-8 Citation Subset: IM |
Copyright Information:
|
Wiley Periodicals, Inc. © 2011 International League Against Epilepsy. |
Affiliation:
|
Child Neurology and Psychiatry, Catholic University, Rome, Italy. fguzzetta@rm.unicatt.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Neuroimaging and neuropathology of Dravet syndrome.
Next Document: Cognitive development in children with Dravet syndrome.