Document Detail


Cognition in Alzheimer's disease: disorders of attention and semantic knowledge.
MedLine Citation:
PMID:  8038583     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Alzheimer's disease leads to a selective decline of cognitive skills, particularly semantic knowledge and visuospatial attention. Recent advances suggest that, although the two systems responsible for these skills can interact, the semantic memory deficit seen in Alzheimer's disease cannot be solely attributed to attention or retrieval deficiencies. This is consistent with a modular view of cognition, which postulates that disruption to these systems is selective in Alzheimer's disease. Cortico-cortical disconnection of association areas may disrupt widespread networks mediating attention and semantic knowledge in Alzheimer's disease.
Authors:
R Parasuraman; A Martin
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Current opinion in neurobiology     Volume:  4     ISSN:  0959-4388     ISO Abbreviation:  Curr. Opin. Neurobiol.     Publication Date:  1994 Apr 
Date Detail:
Created Date:  1994-08-23     Completed Date:  1994-08-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9111376     Medline TA:  Curr Opin Neurobiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  237-44     Citation Subset:  IM    
Affiliation:
Cognitive Science Laboratory, Catholic University of America, Washington, DC 20064.
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MeSH Terms
Descriptor/Qualifier:
Alzheimer Disease / pathology,  physiopathology,  psychology*
Attention*
Brain / pathology,  physiopathology
Cognition*
Humans
Language*
Memory
Models, Neurological
Visual Perception
Grant Support
ID/Acronym/Agency:
NIA AG07569/AG/NIA NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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