Document Detail

Coffee during pregnancy: a reproductive hazard?
MedLine Citation:
PMID:  2014836     Owner:  NLM     Status:  MEDLINE    
Coffee is consumed in large quantities worldwide and any adverse effects would likely have important public health consequences. Because of the widespread exposure to coffee and other caffeine-containing beverages and because teratogenic effects of caffeine have been recorded in several species since 1960, women are concerned that there may be reason to limit their intake of coffee when pregnant. Several human studies on birth defects have been conducted and the overall results do not implicate coffee as a likely human teratogen. However, there is some evidence that consumption of three or more cups of coffee per day may have a modest effect on lowering infant birth weight. Studies of coffee consumption and increased rates of spontaneous abortion and delayed time to conception are inconsistent and conclusions cannot yet be drawn.
S A Narod; S De Sanjosé; C Victora
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  164     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-05-16     Completed Date:  1991-05-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1109-14     Citation Subset:  AIM; IM    
Unit of Mechanisms of Carcinogenesis, International Agency for Research on Cancer, Lyon, France.
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MeSH Terms
Abnormalities, Drug-Induced
Abortion, Spontaneous / chemically induced
Birth Weight / drug effects
Coffee / adverse effects*
Fertility / drug effects
Pregnancy / drug effects*
Reg. No./Substance:

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