Document Detail

Coffee drinking and risk of preterm birth.
MedLine Citation:
PMID:  16391589     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: We analysed the association between coffee drinking before and during the three trimesters of pregnancy and the risk of preterm birth of babies normal for gestational age (NGA) or small for gestational age (SGA). METHODS: Case-control study conducted in University clinics of North Italy. Cases were 502 women who delivered at <37 weeks of gestation. The controls included 1966 women who gave birth at term (>or=37 weeks of gestation) to healthy infants on randomly selected days at the hospitals where cases had been identified. RESULTS: There was inverse association for coffee consumption in the third trimester of pregnancy in SGA cases compared to NGA (heterogeneity test between OR: chi1(2)=5.6811 P<0.05). In comparison with not drinkers, all the ORs of overall intake of caffeine were closed near the unity for both SGA and NGA preterm birth. CONCLUSION: Compared with no consumption, a low consumption of coffee during pregnancy may not have significant effects on preterm birth.
F Chiaffarino; F Parazzini; L Chatenoud; E Ricci; L Tozzi; V Chiantera; C Maffioletti; L Fedele
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  60     ISSN:  0954-3007     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-02     Completed Date:  2006-06-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  610-3     Citation Subset:  IM    
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
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MeSH Terms
Birth Weight / drug effects*
Caffeine* / administration & dosage,  adverse effects
Case-Control Studies
Coffee / adverse effects*
Infant, Newborn
Infant, Premature
Infant, Small for Gestational Age
Middle Aged
Odds Ratio
Pregnancy Outcome
Pregnancy Trimester, Third
Premature Birth / epidemiology*
Risk Factors
Reg. No./Substance:
0/Coffee; 58-08-2/Caffeine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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