| Coexistent myelodysplasia and plasma cell neoplasia. | |
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MedLine Citation:
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PMID: 6849839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The oncogenic effect of alkylating agents, particularly that of melphalan, has been postulated as the most likely cause of myelodysplastic syndrome (MDS) and acute leukaemia in patients with plasma cell neoplasia. Five patients aged between 69 and 79 years were found to have features of MDS at the time of diagnosis of multiple myeloma. In three of these cases MDS transformed into acute leukaemia. These patients had not received any chemotherapy prior to their presentation. The possible importance of these features is discussed. |
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Authors:
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G J Mufti; T J Hamblin; G P Clein; C Race |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: British journal of haematology Volume: 54 ISSN: 0007-1048 ISO Abbreviation: Br. J. Haematol. Publication Date: 1983 May |
Date Detail:
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Created Date: 1983-07-08 Completed Date: 1983-07-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372544 Medline TA: Br J Haematol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 91-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aged Bone Marrow Diseases / complications* Female Humans Leukemia / etiology Male Multiple Myeloma / complications* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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