Document Detail

Coexistent lung carcinoma and active pulmonary tuberculosis in the same lobe.
MedLine Citation:
PMID:  16572076     Owner:  NLM     Status:  MEDLINE    
We observed a rare case of lung carcinoma accompanied by active pulmonary tuberculosis in the same lobe. The chest x-ray of a 49-year-old man revealed an abnormal shadow in the right upper field and a giant bulla in the left upper field. Chest computed tomography (CT) revealed a nodule with consolidation, which was not continuous in the right S3. Bronchoscopically, epidermoid carcinoma existed in the proximal right upper bronchus. In the sputum specimens, the smear was negative, but the polymerase chain reaction of Mycobacterium tuberculosis and culture was positive. Anti-tuberculosis treatments were administered for approximately 4 weeks, but the chest x-ray remained unchanged. Right upper lobectomy with bronchoplasty (wedge resection of the right upper bronchus) was performed, and the anastomosis was covered with an intercostal muscle flap. Lymphadenectomy of the right hilum and mediastum was also performed. Microscopy revealed epidermoid carcinoma in the proximal tumor (pT3N0M0-stage IIB) and epithelioid granuloma with caseous necrosis, granulomatous pneumonia, exudative lesions, and fibrocaseous nodules in the distal lung. After surgery, anti-tuberculosis treatment was resumed.
Motoki Sakuraba; Michihiro Hirama; Akira Hebisawa; Yuzo Sagara; Atsuhisa Tamura; Hikotaro Komatsu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia     Volume:  12     ISSN:  1341-1098     ISO Abbreviation:  Ann Thorac Cardiovasc Surg     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-03-30     Completed Date:  2006-07-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9703158     Medline TA:  Ann Thorac Cardiovasc Surg     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  53-5     Citation Subset:  IM    
Department of Thoracic Surgery, National Hospital Organization Tokyo Hospital, Tokyo Japan.
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MeSH Terms
Antitubercular Agents / therapeutic use
Carcinoma, Squamous Cell / diagnosis,  epidemiology*,  therapy
Lung Neoplasms / diagnosis,  epidemiology*,  therapy
Lymph Node Excision
Middle Aged
Neoplasm Staging
Tuberculosis, Pulmonary / diagnosis,  epidemiology*,  therapy
Reg. No./Substance:
0/Antitubercular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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