Document Detail


Coexistence of plasma cell granulomas of lung and central nervous system.
MedLine Citation:
PMID:  8838375     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A rare case of concurrent plasma cell granulomas (PCG) of the lung and the central nervous system (CNS) is reported. A 30-year-old man was presented with recurrent left headaches lasting for two years. Computerized tomographic (CT) scan and magnetic resonance imaging (MRI) of the head disclosed a process extending from the lateral aspect of the left cavernous sinus to the tentorium cerebelli and the infratemporal fossa through the foramen ovale. At the same time, chest-X ray and CT scan showed three symptomless masses of the pulmonary right lower lobe. Histological examination of cerebral samples and of one of the pulmonary nodules revealed the presence of a fibrous tissue containing numerous lymphocytes and plasma cells as well as remnants of vascular and respiratory structures. Immunohistochemical study proved these cells to be polyclonal. Ultrastructural analysis confirmed the presence of lymphoid cells and failed to disclose any argument for meningioma or histiocytosis X. The differential diagnostic problems of PCG are discussed as well as considerations about clinicopathological features, histogenesis and pathogenesis of inflammatory pseudotumours (IPT).
Authors:
F Le Marc'hadour; J P Lavieille; C Guilcher; E Brambilla; P Y Brichon; J F Lebas; R Charachon; B Pasquier
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pathology, research and practice     Volume:  191     ISSN:  0344-0338     ISO Abbreviation:  Pathol. Res. Pract.     Publication Date:  1995 Oct 
Date Detail:
Created Date:  1996-12-03     Completed Date:  1996-12-03     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7806109     Medline TA:  Pathol Res Pract     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  1038-45     Citation Subset:  IM    
Affiliation:
Department of Pathology, University of Medicine, Grenoble, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Brain Diseases / complications*,  pathology
Dura Mater / pathology
Granuloma, Plasma Cell / complications*,  pathology
Humans
Immunohistochemistry
Lung / radiography
Lymphocytes / ultrastructure
Male
Microscopy, Electron
Plasma Cell Granuloma, Pulmonary / complications*,  pathology,  radiography
Plasma Cells / ultrastructure
Tomography, X-Ray Computed
Comments/Corrections
Comment In:
Pathol Res Pract. 1995 Oct;191(10):1047-8   [PMID:  8838377 ]
Pathol Res Pract. 1995 Oct;191(10):1046   [PMID:  8838376 ]

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