Document Detail


Coexistence of immune thrombocytopenic purpura and idiopathic membranous glomerulonephritis successfully treated with rituximab.
MedLine Citation:
PMID:  20624006     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
We describe here coexistence of immune thrombocytopenic purpura (ITP) and idiopathic membranous glomerularnephritis (IMG) in one individual who presented a decade ago after delivering a macerated dead fetus. Investigations performed then revealed clinical, biochemical and histopathological evidence of IMG. A year later she presented with bleeding diathesis and was diagnosed as ITP. Thereafter, she manifested with several episodes of serious bleeding complications especially in the central nervous system with considerable frequency, inspite of receiving treatment with steroids, intravenous immunoglobulin and cyclosporine. Subsequently, she received six courses of rituximab and went into complete remission. To date, after more than 3.5 years of follow up, she is completely symptom free. Co-existence of IMG and ITP has been reported earlier; however, this is the first instance of successful treatment of both these entities with rituximab.
Authors:
Salam Alkindi; Saif Khan; Dawood Riyami; Mahfooz Farooqi; Anil Pathare
Related Documents :
11325006 - Predictive factors of response to splenectomy in adult chronic idiopathic thrombocytope...
11478456 - Circulating filarial antigens for monitoring the efficacy of ivermectin in treatment of...
23512896 - The effect of recent chemotherapy in aorto-iliac aneurysm repair.
17634496 - Impact of primary prophylaxis with granulocyte colony-stimulating factor on febrile neu...
24392166 - Risk factors for visceral leishmaniasis relapse in immunocompetent patients following t...
23535816 - Impact of a protocol advocating dexmedetomidine over propofol sedation after robotic-as...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Platelets     Volume:  21     ISSN:  1369-1635     ISO Abbreviation:  Platelets     Publication Date:  2010  
Date Detail:
Created Date:  2010-10-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9208117     Medline TA:  Platelets     Country:  England    
Other Details:
Languages:  eng     Pagination:  575-7     Citation Subset:  IM    
Affiliation:
Department of Haematology, College of Medicine & Health Sciences, Sultan Qaboos University Hospital, Muscat, Oman. sskindi@yahoo.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
082390//Wellcome Trust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Primary cutaneous anaplastic large cell lymphoma.
Next Document:  The nitrative and oxidative stress in blood platelets isolated from breast cancer patients: the prot...