Document Detail

Coexistence of diffuse plane normolipaemic xanthoma and amyloidosis in a patient with monoclonal gammopathy.
MedLine Citation:
PMID:  8949445     Owner:  NLM     Status:  MEDLINE    
Diffuse plane normolipaemic xanthomatosis (DPNX) is a well-defined clinicopathological entity that characteristically presents with yellow-orange plaques in the periorbital areas, the neck, the upper trunk and the flexural folds. DPNX has been reported in association with lymphoproliferative disorders and, occasionally, with miscellaneous, probably coincidental disorders. A case of DPNX in a patient with an IgG lambda monoclonal gammopathy and systemic amyloidosis is reported. Clinical and histopathological findings revealed typical features of DPNX and amyloidosis coexisting in the cutaneous lesions. To our knowledge this is the first reported case showing coexistence of xanthoma and amyloidosis in cutaneous lesions in a patient with a monoclonal gammopathy.
G F Buezo; J I Porras; J Fraga; E Sanchez; M Aragües; E Daudén
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  135     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1997-01-14     Completed Date:  1997-01-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  460-2     Citation Subset:  IM    
Department of Dermatology, Universidad Autónoma, Madrid, Spain.
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MeSH Terms
Aged, 80 and over
Amyloidosis / complications*,  pathology
Immunoglobulin G / blood
Paraproteinemias / complications*
Xanthomatosis / complications*,  pathology
Reg. No./Substance:
0/Immunoglobulin G

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