| Coexistence of autoimmune polyglandular syndrome type 2 and diabetes insipidus in pregnancy. | |
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MedLine Citation:
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PMID: 22033074 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Autoimmune polyglandular syndromes are rarely diagnosed conditions characterized by the association of at least 2 organ-specific autoimmune disorders. Very few cases of these syndromes have been described during pregnancy. The authors report a case of a patient diagnosed with autoimmune thyroiditis and a history of HELLP (hemolysis, elevated liver enzymes and low platelet) syndrome in a prior pregnancy. After increasing the levothyroxine dose, she developed Addisonian crisis. Normalization of adrenal cortex function resulted in the appearance of diabetes insipidus. This report shows that pregnancy may influence the course of preexisting endocrine disorders and lead to their unmasking. Although the risk of the development of autoimmune polyglandular syndromes during pregnancy is small, they may pose a serious health problem. The possible presence of these clinical entities should be considered in every woman with 1 or more endocrine disturbances. |
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Authors:
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Robert Krysiak; Malgorzata Samborek |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of the medical sciences Volume: 342 ISSN: 1538-2990 ISO Abbreviation: Am. J. Med. Sci. Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-10-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370506 Medline TA: Am J Med Sci Country: United States |
Other Details:
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Languages: eng Pagination: 433-4 Citation Subset: AIM; IM |
Affiliation:
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From the Department of Internal Medicine and Clinical Pharmacology (rk), Medical University of Silesia, Katowice, Poland; and Department of Gynecology and Obstetrics (ms), The Hospital of the Knights Hospitallers, Katowice, Poland. |
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