Document Detail


Coexistence of the antiphospholipid syndrome and abdominal aortic aneurysm.
MedLine Citation:
PMID:  18300573     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The antiphospholipid syndrome is characterized by recurrent fetal loss, venous and/or arterial thrombosis, and thrombocytopenia associated with elevated titers of lupus anticoagulant and anticardiolipin antibodies. Although thrombosis is the characteristic vascular involvement in APS, the development of vascular aneurysms in patients with APS has been reported. We describe four patients with established APS who developed abdominal aortic aneurysm, and review the literature on previous published cases of arterial aneurysms developing in patients with APS. In addition, we discuss the possible pathophysiological association between APS and the development of this vascular abnormality.
Authors:
Martine Szyper-Kravitz; Arie Altman; Jozélio Freire de Carvalho; Francesca Bellisai; Mauro Galeazzi; Yael Eshet; Yehuda Shoenfeld
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Israel Medical Association journal : IMAJ     Volume:  10     ISSN:  1565-1088     ISO Abbreviation:  Isr. Med. Assoc. J.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-02-27     Completed Date:  2008-03-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100930740     Medline TA:  Isr Med Assoc J     Country:  Israel    
Other Details:
Languages:  eng     Pagination:  48-51     Citation Subset:  IM    
Affiliation:
Center for Autoimmune Diseases and Department of Medicine B, Sheba Medical Center, Tel Hashomer, Israel.
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MeSH Terms
Descriptor/Qualifier:
Aged
Antiphospholipid Syndrome / complications*
Aortic Aneurysm, Abdominal / complications*,  radiography,  therapy
Autoantibodies / blood
Cardiolipins / immunology
Female
Humans
Lupus Coagulation Inhibitor / blood
Male
Middle Aged
Chemical
Reg. No./Substance:
0/Autoantibodies; 0/Cardiolipins; 0/Lupus Coagulation Inhibitor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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