| Coexistence of Crohn's disease in a patient with systemic lupus erythematosus. | |
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MedLine Citation:
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PMID: 22249306 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The concurrence of inflammatory bowel disease with systemic lupus erythematosus (SLE) is rare. The concomitant diagnosis of Crohn's disease and SLE is even more rare. The patient, a 40-year-old woman, was admitted to our hospital because of relapsing episodes of abdominal pain, diarrheas upper and lower extremities arthralgias, Raynaud's phenomenon with positive antinuclear antibodies, and fever for the last 2 years. The patient was diagnosed elsewhere with SLE and treated with hydroxychloroquine. Her medical history also included tonsillectomy and total hip replacement after a car accident. Family history was unremarkable. Physical examination was unremarkable except of very mild pain at lower left abdominal quadrant. Laboratory tests showed erythrocyte sedimentation rate at 32 mm/h, C-reactive protein at 36 mg/dl, positive rheumatoid factor, and increased C3, C4, positive antinuclear antibodies with the presence of anti-Sm and anti-RNP antibodies. Ileocolonoscopy revealed colonic inflammation with ulcers and pseudopolyps. Subsequent biopsies were diagnostic of Crohn's disease. Patient was diagnosed with Crohn's colitis concomitant to systemic lupus erythematosus and was started on therapy with azathioprine 2 mg/Kg, methylprednisolone 16 mg/d with slow tapering, mesalazine 1.5 g/day, and hydroxychloroquine. Patient is in excellent health status on the six-month follow-up. |
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Authors:
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Konstantinos H Katsanos; Paraskevi V Voulgari; Anna Goussia; Panagiotis Oikonomou; Dimitrios K Christodoulou; Alexandros A Drosos; Epameinondas V Tsianos |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-15 |
Journal Detail:
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Title: Rheumatology international Volume: - ISSN: 1437-160X ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8206885 Medline TA: Rheumatol Int Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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1st Division of Internal Medicine and Hepato-Gastroenterology Unit, University of Ioannina, P.O. Box 1186, 45110, Ioannina, Greece. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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