Document Detail

Coenzyme Q10 levels, plasma lipids and peroxidation extent in renal failure and in hemodialytic patients.
MedLine Citation:
PMID:  7752833     Owner:  NLM     Status:  MEDLINE    
Coenzyme Q10 (CoQ10), vitamin E, triglycerides and conjugated dienes were measured in a group of 48 patients on chronic hemodialysis, in 15 uremic patients and in a control group of 10 normal subjects. CoQ10 levels were significantly lower (P < 0.001) in both hemodialytic and uremic patients compared with the normal group whereas triglycerides were significantly higher (P < 0.001) with respect to both normal subjects and uremic patients. Conjugated dienes were significantly higher (P < 0.001) in both hemodialytic and uremic patients with respect to normal subjects. The predialytic values of vitamin E were higher in hemodialytic patients with respect to both normal subjects and uremic patients whereas the postdialytic values were in the normal range. A restoration mechanism of vitamin E after hemodialytic treatment was hypothesized.
S Lippa; L Colacicco; C Callà; G Sagliaschi; A G Angelitti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Molecular aspects of medicine     Volume:  15 Suppl     ISSN:  0098-2997     ISO Abbreviation:  Mol. Aspects Med.     Publication Date:  1994  
Date Detail:
Created Date:  1995-06-21     Completed Date:  1995-06-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7603128     Medline TA:  Mol Aspects Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  s213-9     Citation Subset:  IM    
Istituto di Chimica e Chimica Clinica, Università Cattolica del S. Cuore.
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MeSH Terms
Kidney Failure, Chronic / blood*,  therapy
Lipid Peroxidation*
Lipids / blood*
Middle Aged
Renal Dialysis*
Triglycerides / blood
Ubiquinone / analogs & derivatives*,  blood
Uremia / blood,  therapy
Vitamin E / blood*
Reg. No./Substance:
0/Coenzymes; 0/Lipids; 0/Triglycerides; 1339-63-5/Ubiquinone; 1406-18-4/Vitamin E; 303-98-0/coenzyme Q10

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