| Coeliac disease, gluten-free diet, and malignancy. | |
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MedLine Citation:
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PMID: 789184 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two hundred and two patients with coeliac disease or idiopathic steatorrhoea previously reported from this unit have been reviewed after a further 10 years of follow-up. Of 20 more deaths, 10 were due to malignancy. A separate study was made of all patients with histologically confirmed coeliac disease seen to the end of 1972 and followed up to the end of 1974. Twenty-one of the 43 deaths in this series were due to malignant tumours, of which 13 were reticulum cell sarcomas. There was no evidence that patients showing sub-optimal clinical response to gluten withdrawal or persisting falt jejunal biopsies were more prone to die of cancer. A gluten-free diet did not appear to be effective in preventing malignant complications, but a longer follow-up of patients will be necessary to provide a final answer to this question. |
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Authors:
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G K Holmes; P L Stokes; T M Sorahan; P Prior; J A Waterhouse; W T Cooke |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gut Volume: 17 ISSN: 0017-5749 ISO Abbreviation: Gut Publication Date: 1976 Aug |
Date Detail:
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Created Date: 1976-12-30 Completed Date: 1976-12-30 Revised Date: 2012-05-09 |
Medline Journal Info:
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Nlm Unique ID: 2985108R Medline TA: Gut Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 612-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Celiac Disease / complications*, diet therapy, pathology England Female Follow-Up Studies Gastrointestinal Neoplasms / etiology* Glutens Humans Lymphoma / etiology Lymphoma, Large B-Cell, Diffuse / etiology Male Middle Aged Neoplasms / epidemiology Precancerous Conditions |
| Chemical | |
Reg. No./Substance:
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8002-80-0/Glutens |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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