| Codon usage and intragenic position. | |
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MedLine Citation:
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PMID: 3066998 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Data on codon usage bias in E. coli are re-examined with respect to intragenic position. The bias is less extreme near the beginning than in the rest of the gene, particularly in highly expressed genes. This is contrary to the previous finding that there is a linear decline in codon usage bias with position along weakly expressed genes but little or no change in bias along highly expressed genes. The effect is not confined to genes coding for proteins with leader peptides, as suggested earlier (Burns and Beacham, 1985). There is some evidence of a similar but smaller effect in yeast. |
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Authors:
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M Bulmer |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of theoretical biology Volume: 133 ISSN: 0022-5193 ISO Abbreviation: J. Theor. Biol. Publication Date: 1988 Jul |
Date Detail:
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Created Date: 1989-04-06 Completed Date: 1989-04-06 Revised Date: 2000-12-18 |
Medline Journal Info:
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Nlm Unique ID: 0376342 Medline TA: J Theor Biol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 67-71 Citation Subset: IM |
Affiliation:
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Department of Biomathematics, Oxford, U.K. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Codon* Escherichia coli / genetics Genes, Bacterial RNA, Messenger* |
| Chemical | |
Reg. No./Substance:
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0/Codon; 0/RNA, Messenger |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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