| Cockayne syndrome: MRI correlates of hypomyelination. | |
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MedLine Citation:
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PMID: 3242508 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two siblings with Cockayne syndrome are reported who had most of the stigmata characteristic of the syndrome as it was initially described in 1936. Unusual findings are emphasized, such as the early onset of cataracts and the early detection of peripheral neuropathy. The previously reported autopsy abnormalities in this condition are correlated with the present magnetic resonance imaging findings of mild ventricular enlargement and delay in myelination of the cerebrum and cerebellum. Properly myelinated structures included the basal ganglia, thalamus, internal capsule, splenium, and genu of the corpus callosum. |
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Authors:
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O Dabbagh; K F Swaiman |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric neurology Volume: 4 ISSN: 0887-8994 ISO Abbreviation: Pediatr. Neurol. Publication Date: 1988 Mar-Apr |
Date Detail:
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Created Date: 1989-05-31 Completed Date: 1989-05-31 Revised Date: 2006-05-23 |
Medline Journal Info:
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Nlm Unique ID: 8508183 Medline TA: Pediatr Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 113-6 Citation Subset: IM |
Affiliation:
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Division of Pediatric Neurology, University of Minnesota Medical School, Minneapolis. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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pathology* Cerebral Ventricles / pathology Child, Preschool Cockayne Syndrome / diagnosis*, genetics Dwarfism / diagnosis* Female Humans Infant Magnetic Resonance Imaging* Male Myelin Sheath / pathology* Nerve Fibers, Myelinated / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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