Document Detail

Cochlear threshold assessment using tone-derived action potentials.
MedLine Citation:
PMID:  2383213     Owner:  NLM     Status:  MEDLINE    
An evoked-potential technique has been evaluated which detects whether the cochlea responds to a continuous, low level tone. The technique involves recording the cochlear action potential (AP) response to a suprathreshold probe tone, first in the absence and then in the presence of a continuous masking tone at the same frequency. Subtraction of the masked AP waveform from the unmasked AP yields a 'derived' potential, provided the continuous tone is above the threshold of cochlear sensitivity. Derived AP responses may be recorded with continuous masking tones over 10 dB below the threshold to the probe stimulus. In normally hearing guinea pigs, the mean best derived threshold using a 10-microV response criterion was 7.1 dB SPL, compared to 18.9 dB for conventional AP thresholds. The tone-derived response appears to provide a more sensitive and frequency-specific method for determining cochlear thresholds.
A N Salt; A R Vora
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Audiology : official organ of the International Society of Audiology     Volume:  29     ISSN:  0020-6091     ISO Abbreviation:  Audiology     Publication Date:  1990  
Date Detail:
Created Date:  1990-09-12     Completed Date:  1990-09-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1273752     Medline TA:  Audiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  135-45     Citation Subset:  IM    
Department of Otolaryngology, Washington University School of Medicine, St. Louis, Mo.
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MeSH Terms
Attention / physiology
Audiometry, Evoked Response / instrumentation
Auditory Threshold / physiology*
Cochlear Microphonic Potentials / physiology
Cochlear Nerve / physiology*
Guinea Pigs
Perceptual Masking / physiology
Pitch Discrimination / physiology*
Signal Processing, Computer-Assisted

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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