Document Detail

Cochlear implantation in children with congenital cytomegalovirus infection accompanied by psycho-neurological disorders.
MedLine Citation:
PMID:  22443855     Owner:  NLM     Status:  In-Data-Review    
Abstract Conclusion: Cochlear implantation was effective for deaf children with congenital cytomegalovirus (CMV) infection, but their cochlear implant (CI) outcomes were often impaired, depending on the types of CMV-associated psycho-neurological disorders. Evaluation of cognitive development and autistic tendency of implantees might be useful to predict their CI outcomes. Objectives: To reveal the influence of CMV-associated psycho-neurological disorders on CI outcomes. Methods: This was a retrospective evaluation of 11 implantees with congenital CMV infection (CMV-CIs) and 14 implantees with autosomal recessive hearing loss (genetic-CIs). Results: Nine of 11 CMV-CIs suffered from psycho-neurological disorders; one from attention deficit hyperactivity disorder, two from pervasive developmental disorder, and six from mental retardation. Aided hearing thresholds with CIs in the two groups did not differ, but two autistic and two mentally retarded CMV-CIs showed significantly low scores in speech discrimination tests. Language-Social (L-S) developmental quotients (DQs) evaluated by the Kyoto Scale of Psychological development were improved after the implantation in both groups, but the postoperative increase of L-S DQs was significantly smaller in the CMV-CIs than that of genetic-CIs. Interestingly, the postoperative L-S and Cognitive-Adaptive (C-A) DQs showed statistically significant correlation in all cases except for two autistic CMV-CIs whose L-S DQs were much lower than those expected from their C-A DQs.
Hiroshi Yamazaki; Rinko Yamamoto; Saburo Moroto; Tomoko Yamazaki; Keizo Fujiwara; Masako Nakai; Juichi Ito; Yasushi Naito
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  132     ISSN:  1651-2251     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  England    
Other Details:
Languages:  eng     Pagination:  420-7     Citation Subset:  IM    
Department of Otolaryngology, Kobe City Medical Center General Hospital.
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