Document Detail

Cochlear implant in children with asymptomatic congenital cytomegalovirus infection.
MedLine Citation:
PMID:  19005248     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the development of speech perception and auditory skills after cochlear implantation in deaf children with asymptomatic congenital cytomegalovirus (CMV) infection diagnosed based on the presence of CMV DNA in the neonatal urine. STUDY DESIGN: A prospective study of congenital CMV infection was done between 1996 and 2003. Of 18 children diagnosed with congenital CMV infection, 2 deaf children with asymptomatic CMV infections received cochlear implantation. RESULTS: The 2 deaf children who received cochlear implantation had delayed-onset, progressive sensorineural hearing loss on follow-up audiometric examinations administered at 29 and 39 months of age. After cochlear implantation, their Infant-Toddler Meaningful Auditory Integration Scale scores increased consistently during 36 months of follow-up; these results were similar to those of 5 congenitally deaf children without CMV infection who had cochlear implantation. CONCLUSIONS: Cochlear implantation was effective for improving the development of speech perception and auditory skills in deaf children with asymptomatic congenital CMV infection. There was no significant difference in the development of useful auditory integration between our general pediatric cochlear implant population without CMV infection and those with asymptomatic CMV infection.
Satoshi Iwasaki; Hiroshi Nakanishi; Kiyoshi Misawa; Toru Tanigawa; Kunihiro Mizuta
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-11-13
Journal Detail:
Title:  Audiology & neuro-otology     Volume:  14     ISSN:  1421-9700     ISO Abbreviation:  Audiol. Neurootol.     Publication Date:  2009  
Date Detail:
Created Date:  2009-03-26     Completed Date:  2009-05-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606930     Medline TA:  Audiol Neurootol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  146-52     Citation Subset:  IM    
Copyright Information:
Copyright 2008 S. Karger AG, Basel.
Department of Otolaryngology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu City, Hamamatsu 431-3192, Japan.
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MeSH Terms
Child, Preschool
Cochlear Implantation / adverse effects
Cytomegalovirus Infections / congenital*,  epidemiology
DNA, Viral / urine
Follow-Up Studies
Hearing Aids
Hearing Loss, Sensorineural / etiology
Infant, Newborn
Japan / epidemiology
Pregnancy Complications, Infectious / virology
Prospective Studies
Speech Perception
Reg. No./Substance:
0/DNA, Viral

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