Document Detail


Coccidioides immitis meningitis in a patient with hyperimmunoglobulin E syndrome due to a novel mutation in signal transducer and activator of transcription.
MedLine Citation:
PMID:  19483664     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hyperimmunoglobulin E syndrome (HIES) is a rare primary immunodeficiency characterized by recurrent skin and lung infections. We report the first case of Coccidioides immitis meningitis in a patient with HIES. Coccidioides should be included in the differential diagnosis for central nervous system infections in HIES patients.
Authors:
Annie E Powers; Jeffrey M Bender; Attila Kum?novics; Krow Ampofo; Nancy Augustine; Andrew T Pavia; Harry R Hill
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  28     ISSN:  1532-0987     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-29     Completed Date:  2010-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  664-6     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA. annie.eisinger@hsc.utah.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Amino Acid Substitution / genetics
Amphotericin B / therapeutic use
Antibodies, Fungal / cerebrospinal fluid
Antifungal Agents / therapeutic use
Cerebrospinal Fluid / microbiology
Coccidioides / isolation & purification*
Coccidioidomycosis / diagnosis*,  drug therapy,  microbiology,  pathology
Exons / genetics
Female
Humans
Immunoglobulin G / cerebrospinal fluid
Job's Syndrome / complications*,  diagnosis*,  drug therapy,  pathology
Meningitis, Fungal / diagnosis*,  drug therapy,  microbiology,  pathology
Mutation, Missense*
STAT3 Transcription Factor / genetics*
Sequence Analysis, DNA
Chemical
Reg. No./Substance:
0/Antibodies, Fungal; 0/Antifungal Agents; 0/Immunoglobulin G; 0/STAT3 Transcription Factor; 0/STAT3 protein, human; 1397-89-3/Amphotericin B

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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