| Cocaine use in an urban medical population and the development of angiographically significant coronary artery disease. | |
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MedLine Citation:
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PMID: 16849877 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cocaine is a common drug of abuse in the United States. Although long-term cocaine use has been associated with premature coronary artery disease (CAD), the relationship between cocaine use and the presence of angiographically significant CAD (> or =70%) is not clear. A retrospective analysis of all patients who had undergone cardiac catheterization at an urban medical center over a 1-year period was performed. Five hundred twelve patients were enrolled in the study; 84 (16.4%) had evidence of cocaine use, and 111 (21.7%) were admitted with a myocardial infarction. At the time of cardiac catheterization, 31 (36.9%) cocaine-positive patients had > or =70% stenosis in at least one epicardial vessel, compared with 200 (46.7%) cocaine-negative patients (p = 0.09). Although a trend toward an association was noted on unadjusted analysis, after adjusting for CAD risk factors, cocaine use was not associated with angiographically significant CAD (odds ratio, 0.9; 95% confidence interval, 0.55-1.5; p = 0.7). |
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Authors:
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Amar D Patel; Srikanth Sola; Patrick Caneer; Faiz A Cheema; Divya Gupta; Tarek Helmy; Bobby V Khan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Preventive cardiology Volume: 9 ISSN: 1520-037X ISO Abbreviation: Prev Cardiol Publication Date: 2006 |
Date Detail:
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Created Date: 2006-07-19 Completed Date: 2006-10-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9813731 Medline TA: Prev Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 144-7 Citation Subset: IM |
Affiliation:
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Emory University School of Medicine, Division of Cardiology, Atlanta, GA 30303, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cocaine
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contraindications* Coronary Angiography / methods* Coronary Artery Disease / epidemiology, etiology, radiography* Female Georgia / epidemiology Heart Catheterization / methods Humans Male Middle Aged Narcotics / contraindications* Retrospective Studies Risk Factors Urban Population |
| Chemical | |
Reg. No./Substance:
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0/Narcotics; 50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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