Document Detail


Cocaine-related vascular headaches.
MedLine Citation:
PMID:  1955899     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The records of 21 patients admitted to hospital from January 1985 to December 1988 for acute headache associated with cocaine intoxication were reviewed. Fifteen patients were identified who experienced headaches with migrainous features in the absence of neurological or systemic complications. None of them had a history of cocaine-unrelated headaches or a family history of migraine, and all had a favourable outcome. Three possible mechanisms of cocaine-related vascular headaches are discussed which depend on the interval between cocaine ingestion and development of the headache. We postulate that acute headaches following cocaine use may relate to the sympathomimetic or vasoconstrictive effects of cocaine, while headaches following cocaine withdrawal or exacerbated during a cocaine "binge" may relate to cocaine-induced alteration of the serotoninergic system.
Authors:
A Dhuna; A Pascual-Leone; M Belgrade
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  54     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1991-12-31     Completed Date:  1991-12-31     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  803-6     Citation Subset:  IM    
Affiliation:
Department of Neurology, Hennepin County Medical Center, Minneapolis, MN.
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MeSH Terms
Descriptor/Qualifier:
Adult
Cocaine / adverse effects*
Crack Cocaine / adverse effects
Dose-Response Relationship, Drug
Female
Humans
Male
Migraine Disorders / chemically induced*
Neurologic Examination
Retrospective Studies
Substance Withdrawal Syndrome / diagnosis*
Substance-Related Disorders / complications
Vascular Headaches / chemically induced*
Chemical
Reg. No./Substance:
0/Crack Cocaine; 50-36-2/Cocaine
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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