Document Detail

Cocaine intoxication.
MedLine Citation:
PMID:  22998988     Owner:  NLM     Status:  In-Data-Review    
Cocaine, a natural alkaloid derived from the coca plant, is one of the most commonly abused illicit drugs. Cocaine is commonly abused by inhalation, nasal insufflation, and intravenous injection, resulting in many adverse effects that ensue from local anesthetic, vasoconstrictive, sympathomimetic, psychoactive, and prothrombotic mechanisms. Cocaine can affect all body systems and the clinical presentation may primarily result from organ toxicity. Among the most severe complications are seizures, hemorrhagic and ischemic strokes, myocardial infarction, aortic dissection, rhabdomyolysis, mesenteric ischemia, acute renal injury and multiple organ failure.
Janice L Zimmerman
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Publication Detail:
Type:  Journal Article     Date:  2012-08-30
Journal Detail:
Title:  Critical care clinics     Volume:  28     ISSN:  1557-8232     ISO Abbreviation:  Crit Care Clin     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8507720     Medline TA:  Crit Care Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  517-26     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of Medicine, Weill Cornell Medical College, New York, NY, USA; Critical Care Division, Department of Medicine, The Methodist Hospital, Suite 1001, 6550 Fannin, Houston, TX 77030, USA. Electronic address:
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