Document Detail


Cocaine-induced acute interstitial nephritis: A case report and review of the literature.
MedLine Citation:
PMID:  24475451     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Acute tubular necrosis and pigment induced kidney injury are well described consequences of cocaine abuse. However, acute interstitial nephritis associated with cocaine use has been previously reported in only three patients.
CASE PRESENTATION: We present the case of a 49-year-old man who developed acute kidney injury from biopsy-proven interstitial nephritis after nasal insufflation of cocaine. Unlike prior reports, our patient remained non-oliguric and did not require renal replacement therapy.
CONCLUSIONS: Interstitial nephritis should be considered as a potential cause of acute kidney injury associated with cocaine use. The approach to management of cocaine associated acute kidney injury (AKI) may be different in patients with interstitial nephritis than for those with tubular necrosis or pigment induced renal injury.
Authors:
Rodrigo Alfaro; Nina Vasavada; Paisit Paueksakon; German T Hernandez; George R Aronoff
Publication Detail:
Type:  Journal Article     Date:  2013-07-01
Journal Detail:
Title:  Journal of nephropathology     Volume:  2     ISSN:  2251-8363     ISO Abbreviation:  J Nephropathol     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2014-01-29     Completed Date:  2014-01-29     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  101611182     Medline TA:  J Nephropathol     Country:  Iran    
Other Details:
Languages:  eng     Pagination:  204-9     Citation Subset:  -    
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