Document Detail

Cocaine flakes versus tetracaine/adrenaline solution for local anaesthesia in septoplasty.
MedLine Citation:
PMID:  15626258     Owner:  NLM     Status:  MEDLINE    
The aim of this prospective study was to evaluate the efficacy of cocaine flakes compared to tetracaine with adrenaline solution, as a local anaesthetic for patients undergoing septoplasty. From January 2001 to December 2002, 220 patients underwent septoplasty under local anaesthesia. Patients were randomly classified in group A and group B, where cocaine and the solution of tetracaine/adrenaline were used respectively. A visual analogue scale was used to evaluate the severity of the patients'pain during the procedure. The patients of group B showed a statistically significant lower pain score than patients of group A. We believe that the solution of tetracaine/adrenaline is an effective and safe anaesthetic for patients undergoing septoplasty under local anaesthesia.
John G Bizakis; Vassilios A Lachanas; Emmanuel I Drivas; Dionysios E Kyrmizakis; Emmanuel P Prokopakis; Antonios A Benakis; Emmanuel S Helidonis
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Rhinology     Volume:  42     ISSN:  0300-0729     ISO Abbreviation:  Rhinology     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-12-31     Completed Date:  2005-03-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0347242     Medline TA:  Rhinology     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  236-8     Citation Subset:  IM    
Department of Otorhinolaryngology, University of Crete School of Medicine, Heraklion, Crete, Greece.
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MeSH Terms
Anesthesia, Local*
Anesthetics, Local / administration & dosage*
Cocaine / administration & dosage*
Drug Therapy, Combination
Epinephrine / administration & dosage*
Middle Aged
Nasal Septum / surgery*
Pain Measurement
Pharmaceutical Solutions
Prospective Studies
Tetracaine / administration & dosage*
Vasoconstrictor Agents / administration & dosage*
Reg. No./Substance:
0/Anesthetics, Local; 0/Pharmaceutical Solutions; 0/Vasoconstrictor Agents; 50-36-2/Cocaine; 51-43-4/Epinephrine; 94-24-6/Tetracaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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