| Cocaine and the eye: a historical overview. | |
| | |
MedLine Citation:
|
PMID: 18566545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cocaine was brought to Europe after the discovery of America. In the 19th century, the active component of coca leaves, named cocaine, was extracted and several researchers started experimenting with the substance, describing many physiological and pathological effects of its action. The first scholar to practically demonstrate the possibility of using cocaine solution in medicine, mostly ophthalmology, was Carl Koller. Following this remarkable achievement cocaine became the substance most frequently applied for different types of anaesthesia. Halsted and Hall reported the first successful nerve block of the interior dental nerve with 4% cocaine solution. In 1892, Schleich published the results of his studies in which he used a 0.1-0.2% solution of cocaine hydrochloride intra- and subcutaneously, introducing the so-called infiltration anaesthesia. At the end of the 19th century it was, however, demonstrated that cocaine possessed many undesirable effects, including addiction, which triggered off interest in other, less toxic, anaesthetics. |
| | |
Authors:
|
Andrzej Grzybowski |
Related Documents
:
|
15613515 - John darwall md: birmingham's forgotten children's physician. 15307245 - The lido as venice's refuse tip: dalmatian sheep and the 1819 elephant. 11640125 - The origin of the corpus hippocraticum from ancestors to codices antiqi: the codex vati... 19769685 - Medicinal use of leeches in the texts of ancient greek, roman and early byzantine writers. 21683115 - State of the art in benefit-risk analysis: medicines. 15748075 - Do doctors in north-western somalia follow the national guidelines for tuberculosis man... |
Publication Detail:
|
Type: Historical Article; Journal Article; Portraits Date: 2008-06-20 |
Journal Detail:
|
Title: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde Volume: 222 ISSN: 1423-0267 ISO Abbreviation: Ophthalmologica Publication Date: 2008 |
Date Detail:
|
Created Date: 2008-09-15 Completed Date: 2008-11-03 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0054655 Medline TA: Ophthalmologica Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 296-301 Citation Subset: IM |
Copyright Information:
|
Copyright 2008 S. Karger AG, Basel. |
Affiliation:
|
Department of History of Medicine, Karol Marcinkowski University Medical School, Poznań, Poland. grzyb@am.poznan.pl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anesthetics, Local
/
history* Cocaine / history* Europe History, 15th Century History, 16th Century History, 17th Century History, 18th Century History, 19th Century History, 20th Century History, Ancient History, Medieval Humans Nerve Block / history Ophthalmology / history* United States |
| Chemical | |
Reg. No./Substance:
|
0/Anesthetics, Local; 50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Magnetic resonance spectroscopy performance for detection of dementia, Alzheimer's disease and mild ...
Next Document: Extensive chromosomal polymorphism revealed by ribosomal DNA and satellite DNA loci in 13 Citrus spe...