Document Detail


Cocaine decreases self-control in rats: a preliminary report.
MedLine Citation:
PMID:  1365666     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cocaine abuse is often associated with behavior that takes into account short-term, but not long-term consequences. However, there has been no empirical research concerning the effects of cocaine on self-control (choice of a larger, more delayed reinforcer over a smaller, less delayed reinforcer). In the present research, when food-deprived rats repeatedly chose between a larger, more delayed food reinforcer and a smaller, less delayed food reinforcer, chronic intraperitoneal injections of 15 mg/kg cocaine (but not 10 mg/kg fluoxetine) decreased the rats' choices of the larger, more delayed reinforcer. Cocaine can decrease rats' self-control.
Authors:
A W Logue; H Tobin; J J Chelonis; R Y Wang; N Geary; S Schachter
Related Documents :
14014606 - Transfer across drives of the discriminative effect of a pavlovian conditioned stimulus.
3968636 - Performance maintained by orally delivered phencyclidine under second-order, tandem and...
16812746 - Choice between reliable and unreliable reinforcement alternatives revisited: preference...
3994626 - Suppression of schedule-induced drinking and food-reinforced bar pressing by tail-pinch...
11934506 - Identification and characterization of toxigenic bacillus cereus isolates responsible f...
12493086 - Pre- and postprandial changes in plasma hormone and metabolite levels and hepatic deiod...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Psychopharmacology     Volume:  109     ISSN:  0033-3158     ISO Abbreviation:  Psychopharmacology (Berl.)     Publication Date:  1992  
Date Detail:
Created Date:  1995-02-23     Completed Date:  1995-02-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7608025     Medline TA:  Psychopharmacology (Berl)     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  245-7     Citation Subset:  IM    
Affiliation:
Department of Psychology, State University of New York at Stony Brook 11794.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cocaine / administration & dosage,  pharmacology*
Conditioning, Operant / drug effects*
Fluoxetine / administration & dosage,  pharmacology
Injections, Intraperitoneal
Male
Rats
Reinforcement (Psychology)
Chemical
Reg. No./Substance:
50-36-2/Cocaine; 54910-89-3/Fluoxetine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Selective effects of the D1 dopamine receptor agonist, SKF 38393, on behavior maintained by cocaine ...
Next Document:  Effects of chronic nicotine and haloperidol administration on muscarinic receptor-mediated phosphoin...