| Cocaine decreases self-control in rats: a preliminary report. | |
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MedLine Citation:
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PMID: 1365666 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cocaine abuse is often associated with behavior that takes into account short-term, but not long-term consequences. However, there has been no empirical research concerning the effects of cocaine on self-control (choice of a larger, more delayed reinforcer over a smaller, less delayed reinforcer). In the present research, when food-deprived rats repeatedly chose between a larger, more delayed food reinforcer and a smaller, less delayed food reinforcer, chronic intraperitoneal injections of 15 mg/kg cocaine (but not 10 mg/kg fluoxetine) decreased the rats' choices of the larger, more delayed reinforcer. Cocaine can decrease rats' self-control. |
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Authors:
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A W Logue; H Tobin; J J Chelonis; R Y Wang; N Geary; S Schachter |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Psychopharmacology Volume: 109 ISSN: 0033-3158 ISO Abbreviation: Psychopharmacology (Berl.) Publication Date: 1992 |
Date Detail:
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Created Date: 1995-02-23 Completed Date: 1995-02-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7608025 Medline TA: Psychopharmacology (Berl) Country: GERMANY |
Other Details:
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Languages: eng Pagination: 245-7 Citation Subset: IM |
Affiliation:
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Department of Psychology, State University of New York at Stony Brook 11794. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cocaine / administration & dosage, pharmacology* Conditioning, Operant / drug effects* Fluoxetine / administration & dosage, pharmacology Injections, Intraperitoneal Male Rats Reinforcement (Psychology) |
| Chemical | |
Reg. No./Substance:
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50-36-2/Cocaine; 54910-89-3/Fluoxetine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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