Document Detail

Cocaine associated priapism.
MedLine Citation:
PMID:  10332443     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Cocaine abuse is an ongoing epidemic in the United States. Priapism associated with cocaine use has been reported only twice in the urological literature. To our knowledge we report the first series of priapism associated with cocaine use and the first case associated with the use of this drug in its solid form, known as crack. MATERIALS AND METHODS: We retrospectively reviewed the presentation of 3 patients to our emergency department within the last year. Each patient presented with priapism and no identifiable predisposition other than the use of cocaine within 24 hours, as evident on positive urine toxicology. RESULTS: Each patient delayed seeking treatment, which added to the complexity of therapy. Intracavernosal aspiration and irrigations failed in all 3 cases. Cavernous spongiosal shunting failed in the first 2 cases. Cases 2 and 3 were complicated by the high flow variant of priapism. Case 1 ultimately required partial penectomy for infected, gangrenous, distal penile tissue. CONCLUSIONS: It appears that cocaine can be a cause of refractory priapism and treatment can be challenging. We suggest that urine toxicology screening be considered in such cases. The identification of underlying cocaine abuse is important in preventing priapism recurrence in these patients.
A L Altman; A D Seftel; S L Brown; N Hampel
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  161     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-06-23     Completed Date:  1999-06-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1817-8     Citation Subset:  AIM; IM    
Department of Urology, Case Western Reserve University, Cleveland, Ohio, USA.
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MeSH Terms
Crack Cocaine / adverse effects*
Middle Aged
Priapism / chemically induced*
Reg. No./Substance:
0/Crack Cocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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