Document Detail

Cocaine-associated ischemic colitis.
MedLine Citation:
PMID:  11005354     Owner:  NLM     Status:  MEDLINE    
Cocaine use can result in various gastrointestinal complications, including gastric ulcerations, retroperitoneal fibrosis, visceral infarction, intestinal ischemia, and gastrointestinal tract perforation. We report cocaine-associated colonic ischemia in three patients and review the literature. Including ours, 28 cases have been reported, with a mean patient age of 32.6 years (range, 23 to 47 years); 53.5% were men and 46.5% were women. The interval between drug ingestion and onset of symptoms varied from 1 hour to 2 days. Cocaine is a potentially life-threatening cause of ischemic colitis and should be included in the differential diagnosis of any young adult or middle-aged patient with abdominal pain and bloody diarrhea, especially in the absence of estrogen use or systemic disorders that can cause thromboembolic events, such as atrial fibrillation.
J D Linder; K E Mönkemüller; I Raijman; L Johnson; A J Lazenby; C M Wilcox
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Southern medical journal     Volume:  93     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2000-10-18     Completed Date:  2000-10-18     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  909-13     Citation Subset:  AIM; IM    
Department of Medicine, University of Alabama at Birmingham, USA.
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MeSH Terms
Abdominal Pain / chemically induced
Cocaine-Related Disorders / complications*
Colitis, Ischemic / chemically induced*
Crack Cocaine / adverse effects*
Diagnosis, Differential
Diarrhea / chemically induced
Gastrointestinal Hemorrhage / chemically induced
Middle Aged
Time Factors
Tomography, X-Ray Computed
Reg. No./Substance:
0/Crack Cocaine

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