Document Detail

Cocaine abuse during pregnancy: maternal and fetal implications.
MedLine Citation:
PMID:  2911419     Owner:  NLM     Status:  MEDLINE    
Cocaine abuse during pregnancy has been reported to be associated with a variety of fetal complications and with preterm labor. In this cohort study, pregnancy outcome and health status of infants born to 53 cocaine abusers were compared with those of another group of 100 unexposed women and their infants. Significantly more (P less than .05) pregnancies of abusers were associated with preterm labor. In addition, significantly more (P less than .05) infants had complications at birth (ie, meconium, tachycardia). Infants born to cocaine abusers also had significantly lower (P less than .05) birth weight than infants of controls, and an excess of congenital cardiac anomalies (P less than .01).
B B Little; L M Snell; V R Klein; L C Gilstrap
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  73     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1989 Feb 
Date Detail:
Created Date:  1989-02-23     Completed Date:  1989-02-23     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  157-60     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas.
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MeSH Terms
Birth Weight
Cocaine / adverse effects*
Cohort Studies
Fetal Diseases / chemically induced*
Heart Defects, Congenital / chemically induced*
Infant, Newborn
Meconium Aspiration Syndrome / chemically induced
Obstetric Labor, Premature / chemically induced*
Pregnancy Complications*
Pregnancy Outcome*
Substance-Related Disorders*
Grant Support
507 RR05426-26/RR/NCRR NIH HHS
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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