Document Detail

Cobalt and chromium concentrations in patients with metal-on-metal and other cementless total hip arthroplasty.
MedLine Citation:
PMID:  12070648     Owner:  NLM     Status:  MEDLINE    
We measured the cobalt and chromium concentrations in the serum and urine of 32 patients with current designed metal-on-metal total hip arthroplasty and 43 patients with conventional metal on ultrahigh molecular weight polyethylene (UHMWPE) cementless total hip arthroplasty. The results of our study showed that the serum and urine chromium concentrations increased in 37.5% and 90.6%, respectively, of 32 patients with well-fixed metal articulation (the mean values were 0.09 microg/dl and 2.2 microg/l, respectively) and also increased in 28.6% and 85.7%, respectively, of 7 patients who received metal-on-UHMWPE articulation with loosened acetabular component or stem made of Co/Cr alloy (the mean values were 0.06 microg/dl and 1.6 microg/l, respectively). On the other hand, the serum and urine cobalt concentrations were below the detection limit in all patients.
Katsuhiko Maezawa; Masahiko Nozawa; Tomohiko Hirose; Keiji Matsuda; Motoo Yasuma; Katsuo Shitoto; Hisashi Kurosawa
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Publication Detail:
Type:  Journal Article     Date:  2002-02-28
Journal Detail:
Title:  Archives of orthopaedic and trauma surgery     Volume:  122     ISSN:  0936-8051     ISO Abbreviation:  Arch Orthop Trauma Surg     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-06-18     Completed Date:  2002-09-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9011043     Medline TA:  Arch Orthop Trauma Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  283-7     Citation Subset:  IM    
Department of Orthopaedics, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
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MeSH Terms
Aged, 80 and over
Arthroplasty, Replacement, Hip*
Chromium / analysis*
Chromium Alloys*
Cobalt / analysis*
Hip Prosthesis*
Middle Aged
Prosthesis Failure
Reg. No./Substance:
0/Chromium Alloys; 0/Polyethylenes; 0/ultra-high molecular weight polyethylene; 7440-47-3/Chromium; 7440-48-4/Cobalt

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