Document Detail

Coaxial transthoracic fine-needle biopsy in patients with a history of malignant lymphoma.
MedLine Citation:
PMID:  1549668     Owner:  NLM     Status:  MEDLINE    
Efficacy and safety of coaxial transthoracic fine-needle biopsy were evaluated in 54 patients with a history of malignant lymphoma and new chest lesions. Twenty-one patients had recurrent lymphoma. Correct diagnosis was made in 17 of the 21 patients (81%) after one biopsy. The sensitivity increased to 95% with repeat needle biopsy in three patients. Immunophenotyping (determining phenotype by means of immunologic examination) was essential for a definitive diagnosis of lymphoma in three patients. Non-lymphomatous malignancies were correctly diagnosed in 14 patients. An infectious organism was identified in 11 of 19 patients (58%) with benign lesions. Pneumothorax occurred in eight patients (15%), necessitating placement of a chest tube in two (4%). Mild hemoptysis was observed in four patients (7%). The authors conclude that coaxial transthoracic fine-needle biopsy in patients with a history of lymphoma is safe and accurate. The use of large cutting needles or surgical biopsy can be restricted to patients with false-negative findings at percutaneous biopsy and to patients in whom histologic transformation of lymphoma is suspected.
G R Wittich; K W Nowels; R L Korn; R M Walter; D E Lucas; M D Dake; R B Jeffrey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  183     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1992 Apr 
Date Detail:
Created Date:  1992-04-17     Completed Date:  1992-04-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  175-8     Citation Subset:  AIM; IM    
Department of Radiology, Stanford University Medical Center, CA 94305.
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MeSH Terms
Aged, 80 and over
Biopsy, Needle* / methods
Diagnosis, Differential
Hodgkin Disease / diagnosis,  radiography
Lymphoma / diagnosis*,  radiography
Middle Aged
Neoplasm Recurrence, Local
Prospective Studies
Thoracic Neoplasms / diagnosis*,  radiography
Tomography, X-Ray Computed

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