Document Detail

Coarctation in children. Controlled hypotension using labetalol and halothane.
MedLine Citation:
PMID:  539643     Owner:  NLM     Status:  MEDLINE    
Hypotension was induced with halothane and labetalol, an alpha and beta adrenergic blocking agent, in nine children undergoing operation for postductal coarctation of the aorta. The mean arterial pressure decreased by an average of 30% following labetalol, and in six patients the initial halothane concentration (1%) had to be reduced during this period. The heart rate decreased by an average of 8% after labetalol. Profound beta-blockade did not occur, and operating conditions were considered satisfactory. The usefulness of labetalol in the postoperative period is suggested.
S E Jones
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  34     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:    1979 Nov-Dec
Date Detail:
Created Date:  1980-05-30     Completed Date:  1980-05-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1052-5     Citation Subset:  AIM; IM    
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MeSH Terms
Aortic Coarctation / surgery*
Blood Pressure
Child, Preschool
Heart Rate
Hypotension, Controlled / methods*
Reg. No./Substance:
0/Ethanolamines; 151-67-7/Halothane; 36894-69-6/Labetalol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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