| Coal mine workers' pneumoconiosis (CWP): in vitro study of the release of organic compounds from coal mine dust in the presence of physiological fluids. | |
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MedLine Citation:
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PMID: 9339218 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Solvents like dichloromethane generally are used to yield exhausted extraction amounts of the organic compounds in coals. Leaching of coal mine dust by dichloromethane yields extracts with comparable amounts of alkanes, aromatics, and phenolic compounds. Dominantly phenolic compounds are leached from coal mine dust by aqueous solutions saturated in lecithin because of their high water solubility. High concentrations of phenolic compounds can be extracted from coal mine dust generated from low-rank coals. Phenolic compounds leached by fluids adapted to physiological conditions correlate with high cytotoxicities of the dust from low-rank coals. Adaptation of leaching fluids to physiological conditions allows a more realistic estimation of experiments. Coal mine dust with varying coal content of different ranks can be seen as a parameter reinforcing the cytotoxic potential of coal mine dust. |
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Authors:
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H M Schulz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Environmental research Volume: 74 ISSN: 0013-9351 ISO Abbreviation: Environ. Res. Publication Date: 1997 |
Date Detail:
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Created Date: 1997-11-20 Completed Date: 1997-11-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0147621 Medline TA: Environ Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 74-83 Citation Subset: IM |
Affiliation:
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Baltic Sea Research Institute, Rostock, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Body Fluids
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metabolism* Chromatography, Gas Coal / analysis* Dust / analysis* Humans Hydrogen-Ion Concentration Methylene Chloride / chemistry Mining Occupational Exposure Pneumoconiosis / physiopathology* |
| Chemical | |
Reg. No./Substance:
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0/Coal; 0/Dust; 75-09-2/Methylene Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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