Document Detail


Coagulopathy with piperacillin administration in cystic fibrosis: two case reports.
MedLine Citation:
PMID:  8074918     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two cases are reported of coagulopathy in association with the administration of piperacillin to patients with cystic fibrosis. In both cases the coagulopathy was associated with the development of a serum sickness-like illness with fever, rash and abnormal liver function tests occurring on day 12 and day 16 of treatment, respectively. On withdrawal of the piperacillin, both the serum sickness and the coagulopathy resolved rapidly, without sequelae.
Authors:
P J Rye; G Roberts; R E Staugas; A J Martin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  30     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  1994 Jun 
Date Detail:
Created Date:  1994-10-04     Completed Date:  1994-10-04     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  278-9     Citation Subset:  IM    
Affiliation:
Department of Pulmonary Medicine, Adelaide Children's Hospital, North Adelaide, Australia.
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MeSH Terms
Descriptor/Qualifier:
Blood Coagulation Disorders / blood,  chemically induced*
Blood Coagulation Tests
Child
Child, Preschool
Cystic Fibrosis / drug therapy*
Drug Eruptions / blood,  etiology*
Female
Humans
Liver Function Tests
Piperacillin / adverse effects*
Serum Sickness / blood,  chemically induced*
Chemical
Reg. No./Substance:
61477-96-1/Piperacillin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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