Document Detail


Coagulation problems in liver disease.
MedLine Citation:
PMID:  10850568     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three topics are addressed in this manuscript: (1) the causes of abnormal hemostasis in cirrhosis; (2) the evaluation of hemostasis in cirrhotic patients before invasive procedures or in the presence of bleeding; and (3) the assessment of the effect of recombinant activated factor VII (rFVIIa; NovoSeven, Novo Nordisk A/S, Bagsvaerd, Denmark) on hemostatic function in cirrhotic patients. Laboratory experiments are described that could enhance the understanding of the effect of rFVIIa on blood coagulation during hemostasis in cirrhotic patients.
Authors:
S I Rapaport
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis     Volume:  11 Suppl 1     ISSN:  0957-5235     ISO Abbreviation:  Blood Coagul. Fibrinolysis     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-10-03     Completed Date:  2000-10-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9102551     Medline TA:  Blood Coagul Fibrinolysis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  S69-74     Citation Subset:  IM    
Affiliation:
University of California, San Diego, USA. srapaport@ucsd.edu
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MeSH Terms
Descriptor/Qualifier:
Blood Coagulation*
Blood Coagulation Disorders / blood,  drug therapy,  etiology*
Factor VIIa / therapeutic use
Female
Humans
Liver Diseases / blood*,  complications*
Male
Recombinant Proteins / therapeutic use
Thrombin
Chemical
Reg. No./Substance:
0/Recombinant Proteins; EC 3.4.21.21/Factor VIIa; EC 3.4.21.5/Thrombin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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