| Coagulation, fibrinolysis, platelet and kinin-forming systems during toxemia of pregnancy. | |
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MedLine Citation:
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PMID: 6652168 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The coagulation, fibrinolysis, and platelet and kinin-forming systems were studied during toxemia of pregnancy by multifactorial examinations. In severe toxemia of pregnancy, decreases in extrinsic coagulation factors, platelet, antithrombin III, plasminogen, alpha 2-plasmin inhibitor, and increases in soluble fibrin-monomer complex, fibrin degradation products, beta-thromboglobulin were observed. This suggests that intravascular coagulation, induced probably through the extrinsic pathway and secondary fibrinolysis, is associated with toxemia of pregnancy. Prekallikrein increased during pregnancy but decreased rapidly with onset of labor. The same changes were observed in high molecular weight kininogen, indicating that kinin may be generated, which would contribute to the uterine contraction during labor. The prekallikrein level was significantly low during severe toxemia. |
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Authors:
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M Maki |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Biological research in pregnancy and perinatology Volume: 4 ISSN: 0724-438X ISO Abbreviation: Biol Res Pregnancy Perinatol Publication Date: 1983 |
Date Detail:
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Created Date: 1984-02-14 Completed Date: 1984-02-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8302758 Medline TA: Biol Res Pregnancy Perinatol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 152-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Coagulation Female Fibrinolysis Humans Platelet Count Platelet Function Tests Pre-Eclampsia / blood* Pregnancy Prekallikrein / analysis |
| Chemical | |
Reg. No./Substance:
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9055-02-1/Prekallikrein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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