Document Detail


CoCrMo metal-on-metal hip replacements.
MedLine Citation:
PMID:  23196425     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
After the rapid growth in the use of CoCrMo metal-on-metal hip replacements since the second generation was introduced circa 1990, metal-on-metal hip replacements have experienced a sharp decline in the last two years due to biocompatibility issues related to wear and corrosion products. Despite some excellent clinical results, the release of wear and corrosion debris and the adverse response of local tissues have been of great concern. There are many unknowns regarding how CoCrMo metal bearings interact with the human body. This perspective article is intended to outline some recent progresses in understanding wear and corrosion of metal-on-metal hip replacement both in vivo and in vitro. The materials, mechanical deformation, corrosion, wear-assisted corrosion, and wear products will be discussed. Possible adverse health effects caused by wear products will be briefly addressed, as well as some of the many open questions such as the detailed chemistry of corrosion, tribochemical reactions and the formation of graphitic layers. Nowadays we design almost routinely for high performance materials and lubricants for automobiles; humans are at least as important. It is worth remembering that a hip implant is often the difference between walking and leading a relatively normal life, and a wheelchair.
Authors:
Yifeng Liao; Emily Hoffman; Markus Wimmer; Alfons Fischer; Joshua Jacobs; Laurence Marks
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Physical chemistry chemical physics : PCCP     Volume:  15     ISSN:  1463-9084     ISO Abbreviation:  Phys Chem Chem Phys     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-12     Completed Date:  2013-06-04     Revised Date:  2014-01-23    
Medline Journal Info:
Nlm Unique ID:  100888160     Medline TA:  Phys Chem Chem Phys     Country:  England    
Other Details:
Languages:  eng     Pagination:  746-56     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Alloys / chemistry*
Arthroplasty, Replacement, Hip*
Biocompatible Materials / chemistry*,  therapeutic use
Chromium / chemistry
Cobalt / chemistry
Hip Injuries / therapy
Humans
Molybdenum / chemistry
Nanoparticles / chemistry
Grant Support
ID/Acronym/Agency:
1RC2AR058993-01/AR/NIAMS NIH HHS; RC2 AR058993/AR/NIAMS NIH HHS
Chemical
Reg. No./Substance:
0/Alloys; 0/Biocompatible Materials; 0R0008Q3JB/Chromium; 3G0H8C9362/Cobalt; 81AH48963U/Molybdenum
Comments/Corrections

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