| Co-transfer of embryos derived from cryopreserved and fresh natural cycle oocytes: a pilot study. | |
| | |
MedLine Citation:
|
PMID: 18854108 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Italian legislation regarding reproductive medicine prohibits embryo storage while allowing cryopreservation of supernumerary oocytes. This study evaluated the effect of fresh oocytes obtained from natural unstimulated cycles on the clinical success rates derived from the use of frozen-thawed (FR-TH) oocytes obtained following ovarian stimulation. For 36 women, intracytoplasmic sperm injection was performed on FR-TH oocytes supplemented by a fresh oocyte, if available, derived from a natural cycle in which gonadotrophin-releasing hormone-antagonist was used for premature LH surge control. The retrieval rate of fresh oocytes was 61.1% and survival rate of FR-TH oocytes was 43.6%. The fertilization rate of fresh and FR-TH oocytes was 70% and 52.5%, respectively. Fifty embryos were transferred, 14 of them developed from fresh oocytes and 36 from FR-TH oocytes. Six pregnancies occurred in 10 cycles in which the embryos developed from fresh and FR-TH oocytes (pregnancy rate 60.0%) and two in 12 patients in whom the embryos were obtained from only FR-TH oocytes (pregnancy rate 16.7%) (P < 0.05). In summary, the data demonstrate that the transfer of embryos derived from oocytes cryopreserved following a previous ovarian stimulation and an embryo developed from a fresh one retrieved in natural cycle ensures an excellent clinical outcome. |
| | |
Authors:
|
E Greco; K Litwicka; S Ferrero; F Sapienza; M G Minasi; M Iacobelli; D Zavaglia; Z P Nagy |
Related Documents
:
|
10758188 - Comparison of dysphagics and nondysphagics on pulse oximetry during oral feeding. 20093088 - Two singleton live births after the transfer of cryopreserved-thawed day-3 embryos foll... 3080888 - An in vitro fertilization and embryo transfer pilot study: treatment-dependent and trea... 8743938 - Meiotic spindle organization in fertilized drosophila oocyte: presence of centrosomal c... 10470698 - Effects of plasmodium vivax malaria in pregnancy. 10362918 - How competent are you (or your staff) with shoulder dystocia? |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: Reproductive biomedicine online Volume: 17 ISSN: 1472-6491 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2008 Oct |
Date Detail:
|
Created Date: 2008-10-15 Completed Date: 2009-01-07 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: England |
Other Details:
|
Languages: eng Pagination: 530-6 Citation Subset: IM |
Affiliation:
|
Assisted Reproduction Centre, European Hospital, Rome, Italy. ergreco1@virgilio.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cell Count Cryopreservation* Embryo Transfer / methods* Female Humans Infertility / therapy Male Menstrual Cycle / physiology Oocyte Retrieval / methods* Oocytes* Pilot Projects Pregnancy Pregnancy Rate Sperm Injections, Intracytoplasmic / methods* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Selective vitrification of euploid oocytes markedly improves survival, fertilization and pregnancy-g...
Next Document: Growth differentiation factor-9 and anti-Müllerian hormone expression in cultured human follicles f...