Document Detail


Co-occurrence of chronic hepatitis B virus infection and autoimmune hepatitis in a young Senegalese girl.
MedLine Citation:
PMID:  16825914     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the case of a 9-year-old Senegalese girl with co-occurring wild-type (HBeAg-positive) chronic hepatitis B and antinuclear antibody-positive autoimmune hepatitis. Her HLA haplotype was A1, B8, DRB1*04, DQB1*02. Steriod and lamivudine therapy led to biochemical remission, and reactivation occurred when the patient stopped steroids. Persistent HBV infection due to wild-type virus (likely acquired vertically or early in life, as the mother was HBsAg positive) may have acted as a trigger for autoimmune hepatitis in this young girl.
Authors:
Valerio Nobili; Matilde Marcellini; Rita Devito; Donatella Comparcola; Sandro Vento
Related Documents :
930534 - A longitudinal study on the occurrence of autoantibodies in the course of acute hepatit...
11526534 - Distinct epitopes on formiminotransferase cyclodeaminase induce autoimmune liver cytoso...
15118984 - Differential efficacy of corticosteroids and interferon in a patient with chronic hepat...
7542184 - Autoantibodies in sera from patients with l-tryptophan-associated eosinophilia-myalgia ...
19040604 - Establishment of an enzyme-linked immunosorbent assay system for determining soluble cd...
22403314 - Molecular epidemiologic characterization of enterocytozoon bieneusi in hiv-infected per...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  18     ISSN:  0954-691X     ISO Abbreviation:  Eur J Gastroenterol Hepatol     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-07     Completed Date:  2007-04-03     Revised Date:  2009-10-16    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  927-9     Citation Subset:  IM    
Affiliation:
Department of Liver Diseases, Bambino Gesù Children's Hospital, Rome cSection of Infectious Diseases, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Child
Female
Hepatitis B, Chronic / complications*,  diagnosis,  ethnology
Hepatitis, Autoimmune / complications*,  diagnosis,  ethnology
Humans
Italy
Senegal / ethnology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Gastric epithelial cell proliferation and ras oncogene p21 expression in first-degree relatives of g...
Next Document:  Clinico-histopathological characteristics of clopidogrel-induced hepatic injury: case report and rev...