Document Detail

Co-existing thyrotropin secreting pituitary adenoma and low grade glioma: clinical considerations and literature review.
MedLine Citation:
PMID:  19546848     Owner:  NLM     Status:  MEDLINE    
The authors report an extremely rare co-occurrence of a thyrotropin secreting pituitary adenoma and a low grade glioma. A 35-year old patient was initially misdiagnosed and treated as a case of primary hyperthyroidism till he presented with visual symptoms and seizures. On evaluation he was also found to have a right frontal glioma. They discuss the presentation, clinical and diagnostic implications, treatment options and possible molecular pathways which help us understand the molecular biology of such tumor associations. They review literature of 12 previous indexed reports of pituitary tumors associated with various grades of gliomas. Though there are 3 previous reports of functioning pituitary tumors and gliomas, this is the first report of a thyrotropin secreting pituitary adenoma and an associated low grade glioma.
S V Furtado; R Dadlani; N Ghosal; A Mahadevan; S K Shankar; A S Hegde
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of neurosurgical sciences     Volume:  53     ISSN:  0390-5616     ISO Abbreviation:  J Neurosurg Sci     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-23     Completed Date:  2009-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0432557     Medline TA:  J Neurosurg Sci     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  71-5     Citation Subset:  IM    
Department of Neurosurgery, Sri Satya Sai Institute of Higher Medical Sciences (SSSIHMS), EPIP Area, Whitefield, Bangalore, Karnataka State, India.
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MeSH Terms
Adenoma / pathology,  secretion,  surgery*
Brain Neoplasms / pathology,  surgery*
Glioma / pathology,  surgery*
Neoplasms, Second Primary / pathology,  surgery*
Pituitary Neoplasms / pathology,  secretion,  surgery*
Thyrotropin / secretion
Reg. No./Substance:

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