Document Detail


Co-bedding twins: how pilot study findings guided improvements in planning a larger multicenter trial.
MedLine Citation:
PMID:  17356445     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Co-bedding, a developmental care practice for twins and multiples, has been theorized as a strategy to decrease the adverse neurodevelopmental effects that may be associated with hospitalization. OBJECTIVE: The aim of this study was to determine the feasibility of study design, methods, and the measurement of desired outcomes for the development of a larger multicentered study. RESULTS: Study findings were used to estimate effect size, determine staff and bedside care organization, evaluate feasibility of data collection measures, and identify issues related to recruitment and follow-up. Results were incorporated in the development of a larger multicentered trial grant proposal. DISCUSSION: Pilot studies can play an important role in the development of a competitive grant proposal and efficient conduct of a research trial. Pilot studies strengthen a proposal by providing essential baseline information. A general overview of the purpose of pilot studies is provided here, along with a description of the process of using findings from a pilot study to inform the development of a larger multisite trial. Findings from this pilot study examining the effects of co-bedding on twins and their parents are used to revise the research protocol for a larger multisite trial. These changes, which lead to improvement to the protocol, and the rational for these changes are highlighted.
Authors:
Kathryn Hayward; Marsha Campbell-Yeo; Sheri Price; Della Morrison; Robin Whyte; Heather Cake; Jocelyn Vine
Related Documents :
8341865 - Evaluation of multicentre clinical trial data using adaptations of the mosteller-tukey ...
23263365 - Mechanics of the mitral valve: a critical review, an in vivo parameter identification, ...
17689815 - A simple method to correct for the design effect in systematic reviews of trials using ...
1786325 - Exact statistical inference for group sequential trials.
17371125 - Constructing personality scales under the assumptions of an ideal point response proces...
15990275 - Modelling brain emergent behaviours through coevolution of neural agents.
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Nursing research     Volume:  56     ISSN:  0029-6562     ISO Abbreviation:  Nurs Res     Publication Date:    2007 Mar-Apr
Date Detail:
Created Date:  2007-03-14     Completed Date:  2007-04-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376404     Medline TA:  Nurs Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  137-43     Citation Subset:  AIM; IM; N    
Affiliation:
Dalhousie University School of Nursing, Halifax, Nova Scotia, Canada. kathryn.hayward@dal.ca
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Attitude to Health
Bias (Epidemiology)
Data Collection / standards
Effect Modifiers (Epidemiology)
Feasibility Studies
Female
Follow-Up Studies
Humans
Incubators, Infant*
Infant, Newborn
Male
Multicenter Studies as Topic* / nursing,  standards
Neonatal Nursing / methods*,  standards
Nursing Evaluation Research / organization & administration*
Parents / psychology
Patient Selection
Pilot Projects*
Planning Techniques
Questionnaires
Research Design / standards
Sample Size
Self Efficacy
Twins*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Methods to optimize recruitment and retention to an exercise study in Chinese immigrants.
Next Document:  Bariatric and body-contouring surgery: a continuum of care for excess and lax skin.