Document Detail

Co-bedding twins: how pilot study findings guided improvements in planning a larger multicenter trial.
MedLine Citation:
PMID:  17356445     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Co-bedding, a developmental care practice for twins and multiples, has been theorized as a strategy to decrease the adverse neurodevelopmental effects that may be associated with hospitalization. OBJECTIVE: The aim of this study was to determine the feasibility of study design, methods, and the measurement of desired outcomes for the development of a larger multicentered study. RESULTS: Study findings were used to estimate effect size, determine staff and bedside care organization, evaluate feasibility of data collection measures, and identify issues related to recruitment and follow-up. Results were incorporated in the development of a larger multicentered trial grant proposal. DISCUSSION: Pilot studies can play an important role in the development of a competitive grant proposal and efficient conduct of a research trial. Pilot studies strengthen a proposal by providing essential baseline information. A general overview of the purpose of pilot studies is provided here, along with a description of the process of using findings from a pilot study to inform the development of a larger multisite trial. Findings from this pilot study examining the effects of co-bedding on twins and their parents are used to revise the research protocol for a larger multisite trial. These changes, which lead to improvement to the protocol, and the rational for these changes are highlighted.
Kathryn Hayward; Marsha Campbell-Yeo; Sheri Price; Della Morrison; Robin Whyte; Heather Cake; Jocelyn Vine
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Nursing research     Volume:  56     ISSN:  0029-6562     ISO Abbreviation:  Nurs Res     Publication Date:    2007 Mar-Apr
Date Detail:
Created Date:  2007-03-14     Completed Date:  2007-04-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376404     Medline TA:  Nurs Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  137-43     Citation Subset:  AIM; IM; N    
Dalhousie University School of Nursing, Halifax, Nova Scotia, Canada.
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MeSH Terms
Attitude to Health
Bias (Epidemiology)
Data Collection / standards
Effect Modifiers (Epidemiology)
Feasibility Studies
Follow-Up Studies
Incubators, Infant*
Infant, Newborn
Multicenter Studies as Topic* / nursing,  standards
Neonatal Nursing / methods*,  standards
Nursing Evaluation Research / organization & administration*
Parents / psychology
Patient Selection
Pilot Projects*
Planning Techniques
Research Design / standards
Sample Size
Self Efficacy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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