Document Detail

Cluster of acute hemorrhagic appendicitis among high school students in Wuhan, China.
MedLine Citation:
PMID:  15249235     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Features of a cluster of acute appendicitis that occurred among a high school student population in China were investigated. METHODS: Epidemiologic data, medical records, and histologic slides of resected appendices were examined. RESULTS: During a period between April 10, 1997, and June 11, 1997, 11 cases occurred in a high school, with 10 cases among 290 students enrolled at the time. From the end of the initial cluster until June, 2000, 20 additional cases were encountered. Female cases (6.5%) are more frequent than male cases (1.9%). There was a clustering pattern. Many patients had a history of mutual contact before the onset of symptoms. Pathologically, the resected appendices exhibited diffuse or focal hemorrhages in the lamina propria or within hyperplastic lymphoid follicles, and infiltration by eosinophils and by lymphocytes. Appendical tissues were examined using immunohistochemistry, but no etiologic agent was identified. CONCLUSIONS: This cluster of acute appendicitis represented a special kind of appendicitis, with features of an infectious disease in epidemiology.
Yi Guo; Shu-Yuan Xiao; Hong Yan; Ning-Dong Sun; Ming-Sen Jiang; Dong-Ying Liu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of surgery     Volume:  188     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-07-13     Completed Date:  2004-08-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  115-21     Citation Subset:  AIM; IM    
Department of Pathology and WHO Collaborating Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX, USA.
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MeSH Terms
Appendicitis / complications,  epidemiology*,  pathology
China / epidemiology
Disease Outbreaks*
Hemorrhage / etiology,  pathology
Sex Distribution

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