| Clozapine-withdrawal catatonia. | |
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MedLine Citation:
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PMID: 20587767 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Case reports in which abrupt clozapine discontinuation led to a return of psychosis, autonomic instability, or catatonia have been previously presented in the literature. OBJECTIVE: The authors report on symptom presentation and resolution in a case of abrupt withdrawal of clozapine medication. METHOD: The authors describe the condition and history of the patient, a 49-year-old woman with schizophrenia, the medical support she received, and the re-initiation of her clozapine medication. RESULTS: Symptoms of catatonia and autonomic instability resolved by Day 4 of treatment. CONCLUSION: Patients and their caregivers need to be educated about the effects of abrupt cessation of clozapine administration. |
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Authors:
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Mitali Wadekar; Saba Syed |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Psychosomatics Volume: 51 ISSN: 1545-7206 ISO Abbreviation: Psychosomatics Publication Date: 2010 Jul-Aug |
Date Detail:
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Created Date: 2010-06-30 Completed Date: 2010-10-25 Revised Date: 2012-04-24 |
Medline Journal Info:
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Nlm Unique ID: 0376506 Medline TA: Psychosomatics Country: United States |
Other Details:
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Languages: eng Pagination: 355-355.e2 Citation Subset: IM |
Affiliation:
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Dept. of Psychiatry and Biobehavioral Sciences, UCLA, UCLA-Psychiatry Residency Program Education Office (116A3), 16111 Plummer St., Bldg. 10, North Hills, CA 91343, USA. mitaliwadekar@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antipsychotic Agents
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adverse effects*,
therapeutic use Catatonia / chemically induced*, drug therapy, psychology Clozapine / adverse effects*, therapeutic use Female Follow-Up Studies Humans Middle Aged Schizophrenia / drug therapy* Schizophrenic Psychology Substance Withdrawal Syndrome / drug therapy*, psychology Suicide, Attempted / psychology |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 5786-21-0/Clozapine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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