Document Detail

Clozapine-induced effuso-constrictive pericarditis. Case report and review of the literature.
MedLine Citation:
PMID:  17085936     Owner:  NLM     Status:  MEDLINE    
Clozapine is a widely used antipsychotic medication and is effective against both positive and negative symptoms of schizophrenia. However, clozapine use should be monitored closely due to its side effects profile. The main side effects include cardiorespiratory symptoms, seizures and agranulocytosis. We report a case of effuso-constrictive pericarditis soon after being started on clozapine therapy, whose symptoms improved after discontinuation of clozapine. The literature is reviewed and importance of monitoring is discussed.
S Rathore; N D Masani; P O Callaghan
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-11-02
Journal Detail:
Title:  Cardiology     Volume:  108     ISSN:  1421-9751     ISO Abbreviation:  Cardiology     Publication Date:  2007  
Date Detail:
Created Date:  2007-10-04     Completed Date:  2007-10-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  183-5     Citation Subset:  IM    
Copyright Information:
2007 S. Karger AG, Basel
The Cardiothoracic Centre, Liverpool, UK.
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MeSH Terms
Antipsychotic Agents / adverse effects*,  therapeutic use
Clozapine / adverse effects*,  therapeutic use
Middle Aged
Pericarditis, Constrictive / chemically induced*
Schizophrenia / drug therapy
Reg. No./Substance:
0/Antipsychotic Agents; 5786-21-0/Clozapine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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